Tom Izzo said the two players tested positive "four days ago".
"It saddens me of course because Mady was a guy that was starting to play more minutes and we knew with Iowa and IL coming up size would help", Izzo said. "This virus does not discriminate and I can't emphasize enough how important it is to wear a mask, wash your hands and follow protocols".
Michigan State-Iowa originally scheduled for Thursday night is off for now due to COVID cases within the Spartans program. The team is tested every day for COVID-19.