COVID-19 survivors suffer long-term effects after recovery: Lancet

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"We're seeing in our post-COVID recovery clinics that people are coming in with cardiomyopathy and neuropathies and cognitive changes". Do the symptoms completely disappear, or is there a possibility of experiencing some symptoms after recovery?

"The decline of neutralizing antibodies observed in the present study and other studies raises concern for SARS-CoV-2 reinfection", the researchers wrote, adding that "the risk of re-infection should be monitored for patients who present with compatible symptoms of Covid-19".

China has been accused of initially covering up the outbreak that first emerged in the central city of Wuhan in late 2019, which critics say delayed China's initial response and allowed COVID-19 to spread globally. The numbers of these bacteria remained low in the samples collected up to 30 days after infected patients had cleared the virus from their bodies.

For the study, the researchers obtained blood and stool samples and medical records from 100 hospitals of patients with laboratory-confirmed Covid-19 infection between February and May 2020.

The study reveals the most common symptoms patients continue to feel is fatigue or muscle weakness. Patients had a median age of 57.0 (IQR 47.0-65.0) years and 897 (52%) were men. Researchers began in-person follow-up visits with this group after an average of 186 days post-hospitalization.

Their study included patients discharged from Jin Yin-tan Hospital from January 7 to May 29, 2020 who were interviewed with a series of questionnaires for evaluation of symptoms and health-related quality of life. They also underwent physical examinations, lab tests, and a six-minute walking test to gauge patients' endurance levels.

The coronavirus also has made a noticeable impact on patients' lung and kidney function.

Almost 400 patients also underwent further tests, including an assessment of their lung function, and 94 patients whose blood antibody levels were recorded at the height of the infection received a follow-up test.

According to the study, 41 per cent of the 390 patients tested for lung function experienced reduced lung function.

The severity of Covid-19 was classified as mild in the absence of x-ray evidence of pneumonia; moderate if pneumonia with fever and respiratory tract symptoms were detected; severe if patients found it very hard to breathe normally; and critical if they needed mechanical ventilation or experienced organ failure requiring intensive care. For patients at severity scale 4 (who required oxygen therapy) and those at scale 3 (who did not require oxygen therapy) the figures were 29 per cent and 22 per cent, respectively.

Huang Chaolin, vice-president of Jinyintan Hospital who recovered from COVID-19, said in the interview that recovered patients may experience coughing and shortness of breath shortly after being discharged from the hospital, but these symptoms can lessen with time and may eventually disappear.



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