Oxford-AstraZeneca vaccine safe for older adults, results show

According to details, the vaccine that is undergoing the third phase of a clinical trial in Pakistan has shown positive results with 95 percent recovery rate of the patients who were about to be shifted on a ventilator. The issue of advance purchase commitment for vaccines, including pricing, was also discussed in a recent meeting attended by NITI Aayog Member (Health) Vinod Paul, Principal Scientific Advisor to the government K VijayRaghavan and Union Health Secretary Rajesh Bhushan.

"We expect emergency authorisation for Oxford-Astrazeneca vaccine to be sought in the UK". Another US biotechnology company, Moderna, said it too would apply for the right to emergency use to the US Food and Drug Administration (USFDA) in the coming weeks. Meanwhile, five vaccines are under different phases of clinical trials in India.

The Oxford-AstraZeneca COVID-19 vaccine candidate, called AZD1222 or ChAdOx1 nCoV-19, had been among the front-runners in global efforts to develop shots to protect against infection with the novel coronavirus, or SARS-CoV-2. A source said, "It has been decided that the team constituted by the Prime Minister's Office will set the principles of approving the use of vaccine task force (VTF) in an emergency".

Serum third stage testThe Serum Institute of India is now conducting Phase III trials of the Oxford-Astrogenica vaccine, while Bharat Biotech and ICMR have begun Phase III trials of indigenously developed covicin. The most common symptom was injection-site pain, which is in accordance with previous findings for another Covid-19 vaccine from Sinopharm, Beijing.

In Sao Paulo, Brazil's largest state, local authorities have signed a deal with China's Sinovac Biotech Ltd to test and produce a vaccine locally.

It was also agreed at the meeting that one point of contact will be responsible for examining and responding to authorisations given (or in the pipeline), globally, the source said.

But rival drugmakers Pfizer Inc, BioNTech and Moderna Inc have in the past 10 days edged ahead, releasing data from late-stage COVID-19 vaccine trials that shows more than 90% efficacy.

Older adults have an increased risk of COVID-19, so it's crucial that vaccines against the disease are effective in this age group.



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