In a statement on Monday, researchers at Imperial College London and Oxford University said a trial involving 30 people would test vaccines developed by both institutions when participants inhale the droplets in their mouths, which would directly target their respiratory systems. AstraZeneca had paused its trials on Tuesday after observing a single event of an unexplained illness that occurred in the United Kingdom phase III trial.
The Briton who suffered the potentially risky side effects is expected to recover, but Oxford University says it "cannot disclose medical information about the illness for reasons of participant confidentiality".
Close on the heels of the AZ statement, Serum Institute of India said, "Once (the) DCGI (Drug Controller General of India) gives us the permission to restart the trials in India, we will resume the trials".
The Serum Institute of India is working with five other global pharmaceutical firms, including AstraZeneca and Novavax, to develop a coronavirus vaccine, and may partner with Russia's Gamaleya Research Institute to produce the "Sputnik" vaccine. "At the same time, the suspension of trials clearly showed the fallacy of the approach, when entire countries exclusively rely on novel and untested platforms when choosing a vaccine for widespread use, including the use of a monkey adenovirus vector or mRNA technology", Dmitriev said in a press release. In fact, it has been reported this same vaccine trial was temporarily halted back in July after a subject was diagnosed with multiple sclerosis.
This comes on the heels of an announcement from the CDC earlier this month, which instructed public health officials in all 50 states and five large cities of the U.S.to prepare to distribute a viable coronavirus vaccine to health care workers and other high-risk groups. It's not always a fast and straight road. "We need to end their greed". The next steps on the vaccine trial would depend on details from the data safety monitoring board, she said, in a briefing before the MHRA had cleared the vaccine for trials.
British scientists are beginning a small study comparing how two experimental coronavirus vaccines might work when they are inhaled by people instead of being injected. It's a blinded study so that the participants and the doctors don't know who has received what.
Pfizer's coronavirus vaccine could be distributed to Americans before the end of the year if found to be safe and effective, CEO Albert Bourla said Sunday.
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