The game started out with Liverpool pushing forward, trying to get the crucial away goal they needed to progress after a 0-0 draw at Anfield in the first leg.
Despite all the focus on Manchester City chasing a quadruple, Liverpool are still pursuing a Premier League-Champions League double - something not achieved since Manchester United managed it in 2008 - and with Van Dijk in such peerless form, you can not write them off.
While many may consider Mane to have been Man-of-the-Match, Van Dijk managed to put in another colossal performance in defence.
In fact, he was so impressive, that even John Henry had to tweet about him.
Robert Lewandowski is one of the best strikers in the world but the Dutch defender made him look average throughout. He also scored a headed goal, Liverpool's crucial second, prompting Klopp to highlight his vast value to this team.
"I really think this club deserves to have awareness again".
He re-posted a tweet which read: "75% of the earth is covered by water".
Van Dijk will be expected to retain his spot in the starting XI against the Cottagers and Johnson believes he has mastered the art of defending.
Liverpool past year had an English game against City, I was not here, but it could happen again. "Still this was not a great game of football".
"As a player you don't want to see others around you panicking and that's one thing I've never seen him do", Johnson told talkSPORT.
"We were unlucky on their equaliser, but we got the job done and we're into the last eight".
And Jurgen Klopp claimed he could "write a book" about Van Dijk's skills. Van Dijk possesses all of the strengths of Hummals and Sule but none of the weaknesses, and he did not give Lewandowski an inch of space all night.
Mane was a thorn in the Bavarians' side for most of the night, and his first goal was of the highest quality. "He's so good on the ball, so calm, big and strong - there's not really a weakness in his game at the moment".
"Today we didn't play like in the Bundesliga, of course I don't know why".
Busch captures 52nd career Cup victory with Phoenix win
Busch is now close to hitting the magic number of 200 NASCAR victories, which would tie him with Richard Petty for the most ever. It would have been awesome to start out this year two weekend sweeps in a row. "This is what we deserve".
MLB, MLBPA Agree To Single Trade Deadline Starting In 2019
What had been a 26th player for certain day-night doubleheaders through August 31 will become a 27th player in those situations. From September 1st through the end of the championship season, all Clubs must carry 28 players on the active roster.
Soldiers 'cannot live in constant fear of prosecution'
Police also investigated whether any suspects perjured themselves while giving evidence to the long-running Bloody Sunday inquiry. We wanted to meet with them personally to explain the prosecution decisions taken and to help them understand the reasons.