Griffin got the game off to a strong start with 15 points in the first quarter. Reggie Bullock, another former first-round pick of the Clippers, scored 17 points for the Pistons, who had lost nine of 11.
"There was a lot of hype coming into this game and I was looking forward to it, but I'm glad that it's over", Griffin said.
Griffin averaged 21.6 points, 9.3 rebounds and 4.2 assists in 8 seasons in Los Angeles. Lou Williams added 22 points, and Montrezl Harrell had 21 points and nine rebounds.
The Clippers tied the game up at 97 on a 3-pointer from Williams. Griffin did not even look at Ballmer before breaking into a trot and heading for the locker room.
The Clippers went on a run themselves but ultimately came up short - a steal from Bruce Brown with 21.2 second remaining followed by a pair of free throws sealed the deal for the Pistons.
The Pistons maintained a 65-54 advantage at the half, then scored the first five points of the second half to take their biggest lead at 70-54.
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