Experimental treatment may desensitize allergic kids to peanuts

Peanut kernels and shell

Even better, their reaction to this 100-fold dose at the end of the study was milder than their reaction to the initial dose at the beginning of the study. He had just completed a year-long clinical trial of an oral immunotherapy regimen that aims to reduce children's sensitivity to peanut allergens by gradually exposing them to peanut protein over the course of six months, starting with minute amounts that are carefully measured and increased incrementally under medical supervision as tolerance develops. Twenty-five percent of children who had received AR101 experienced moderate symptoms during a food challenge at the end of the treatment, versus 59 percent of participants who had been given a placebo.

The study, the largest OIT investigation to date, focused on 496 participants between the ages of 4 and 17, all of whom were highly allergic to peanuts.

Peanut allergy sufferers have been given new hope following the results of a landmark study.

Jonathan Hourihane, professor of paediatrics and child health at UCC, said the trial was revolutionary and that 67 per cent of those on the treatment could tolerate peanuts afterwards.

However, the discovery is revolutionary because the study reports that there are now no approved treatment options for patients who are at risk for unpredictable and life-threatening allergic reactions to peanuts.

"Her allergy was very severe, so even a small amount of peanut could lead to a very serious reaction".

Peanut allergies can be deadly-and a complicated practical issue to deal with, as anyone with personal experience with such an allergy (and there's about one million kids in the US who have one) well knows.

Sophie Pratt, 44, from north London, enrolled her six-year-old daughter Emily onto the study.

- There could soon be a new treatment option to help millions of people who suffer from peanut allergies. "Now, we have a safety net that we can provide to kids that will prevent an allergic reaction if they accidentally take a bite of a peanut-containing food". Again, this isn't meant as a be-all-end-all solution to peanut allergies; it's simply meant to protect patients against life-threatening reactions (anaphylactic shock) when they unknowingly come into contact with a small dose of peanut. "The impact on our family life was huge".

People rarely outgrow the allergy which is the most common cause of food allergy deaths.

Related:

Comments

Latest news

LeRoy Butler named a Pro Football Hall of Fame semifinalist
He's now the only offensive or defensive player from the 1990s All-Decade Team that has yet to be a finalist for enshrinement. NFL Honors will be taped earlier that evening at the Fox Theatre in Atlanta from 5-7 p.m.

Make Siri Suck Less By Telling It to Use Google Assistant
Once you're all set up, you can then create Siri Shortcuts which call on Google Assistant Routines you've already created. Once done, you can trigger Assistant by simply saying "Hey Siri" followed by the voice phrase you recorded.

LG WK9 Good Show Specs, Value Formally Revealed
To respect your privacy, LG has also fitted the XBOOM AI ThinQ WK9 with a switch at the top to mute the microphone and the camera. Now, the company has finally revealed some launch details of the upcoming device, including specs and pricing.

Devin Lima, LFO Singer, Dead at 41
LFO , a popular 90s group, was best known for their hits, " Summer Girls ", "Girl on TV", and "Every Other Time". "My son has passed away ", his mother Filomena Lima, told Us Weekly . "The family is not good".

Afghans mourn as death toll in Kabul attack jumps to 55
Dozens of ambulances rushed to the site of the blast, according to videos posted on Twitter . In August, at least 34 people were killed in an attack which targeted an education center.

Other news