They urged Senators not to confirm the nomination of Kavanaugh given sexual assault allegations against him. Though, when asked how sure she was that Kavanaugh was the boy who attacked her, Dr. Ford said "100%".
In 1881, Stanley Matthews, President James Garfield's pick to replace Justice Noah Swayne, won confirmation by a single vote, 24 to 23 (51.06%). Still, Collins said, the allegations "fail to meet the "more likely than not" standard", and "I do not believe that these charges can fairly prevent Judge Kavanaugh from serving on the court".
Confirming Mr Kavanaugh to the lifetime post would hand Mr Trump a clear victory and tip the balance on the court to a 5-4 majority in favour of conservatives in possible legal battles over contentious issues such as abortion rights, immigration, and Mr Trump's attempt to ban transgender people from the U.S. military. He denied those accusations, as well as Ford's, in angry testimony to a Senate committee.
Kavanaugh's confirmation would ensure a conservative majority on the court for years and perhaps decades to come - and hand Trump a huge political victory.
Kavanaugh's fate remained unclear early Friday, as a handful of key senators who hold the keys to his success had yet to say if they were prepared to support the judge. He was the sixth Supreme Court nominee she has considered and the sixth she has approved.
Manchin announced he would vote to confirm Kavanaugh, in spite of "reservations" about the allegations and the nominee's temperament.
But when all the votes were cast, ultimately Murkowski voted no and Collins voted yes. Kavanaugh deserves a presumption of innocence, Collins said, and allegations by Christine Blasey Ford and other women did not reach a threshold of certainty.
The Kavanaugh fight has riveted Americans just weeks before November 6 midterm elections in which Democrats are trying to take control of Congress from the Republicans.
He voted to advance the nominee, then told reporters that barring any dramatic changes, he will vote yes on Kavanaugh's confirmation.
Following Friday's vote, Mr Trump tweeted that he was "very proud". Like the Bar Association, the professors cited the judge's behavior at last week's testimony.
His nomination became a flashpoint in the #MeToo social media movement against sexual harassment and assault.
The dramatic Senate floor announcement by perhaps the chamber's most moderate Republican ended the suspense over a tortuous, election-season battle that had left Kavanaugh's fate in doubt for almost a month after the first accusation against him.
Murkowski described her decision to oppose Kavanaugh as "agonizing", and said that while she hopes he will be a "neutral arbiter" on the court, she "could not conclude that he is the right person for the court at this time".