No. 7 Karolina Pliskova is the other top-eight-seeded woman left in the draw.
Which other top seeds will be joining them?
The match was relatively straightforward for the 17-time grand slam victor, although he received a pair of time violation warnings from a chair umpire he has clashed with in the past, Carlos Bernardes. "Hopefully it's nothing that will concern me", said Djokovic.
While there have been plenty of questions about the soccer World Cup in media conferences at Wimbledon this year, Nick Kyrgios was happy to field one on basketball on Thursday. I was just missing some balls, some easy balls, giving him a chance to come back.
Argentine Juan Martin del Potro beat Feliciano Lopez 6-4, 6-1, 6-2.
Victory for the towering Argentine meant that he matched compatriot David Nalbandian's tally of 19 Wimbledon match victories and 86 grand-slam match wins.
Britain's female hope Johanna Konta failed in her second round match as Dominika Cibulkova claimed a dominant 6-3, 6-4 win.
"I think we both played pretty well and it was a pretty close match". "It's a good court, but. of course, bigger courts are nicer".
Meanwhile, Ekaterina Makarova of Russian Federation has become the first player to reach the fourth round at Wimbledon. "Yes!" - several times after winning a big point. I don't want. Sorry. I don't see a countdown.
Women's French Open victor Simona Halep avoided being upset.
Three of the next four games would be breaks, including Muguruza failing to serve out the set at 5-4.
John Isner, the U.S. ninth seed, saved two match points, fired 64 aces and 88 winners to defeat Belgian qualifier Ruben Bemelmans 6-1, 6-4, 6-7 (6/8), 6-7 (3/7), 7-5.
"I went on court with the determination to play at the right intensity". I love video games. I'm working on it, but these kind of matches and these kind of situations I need it much more.
Nonetheless, the form the Belgian showed to upset Muguruza shone through to the end of the match, as she won the last four games to move safely through to a round of 16 meeting with No.14 seed Daria Kasatkina.
Kerber has a 2-1 head-to-head record against the Japanese player, with all three matches played on hard courts.
The world No.47, who won her second career singles title in Budapest in February, was introduced to the sport by her older brother Sean, and has a twin brother named Brett.
"I'm actually looking forward to playing against her on grass".
"I was ready to play and that is it, nothing to say", she said.
"We had really tough matches".
But she clung on and went on win the next 10 games, locking out her opponent from the contest entirely.
Men's third seed Marin Cilic was Thurday knocked out of Wimbledon following a shock five-set defeat to Argentina's Guido Pella in the second round.
"In the fourth set he broke my serve but I was calm".
Eugenie Bouchard of Canada, who lost to Kvitova in the 2014 Wimbledon final, lost to 17th-seeded Ashleigh Barty 6-4, 7-5. The Spaniard served 60 percent for points and had 19 overall winners in the set while limiting the errors to just seven.
Thai schoolboys not ready for underwater escape
After several days of searching, rescuers found all 13 people alive but face a challenge to extract them from the situation . Thousands of volunteers, members of the Thai military, and worldwide rescue experts are participating in the search effort.
Three more dead as record heavy rain hits Japan
A resident struggles to cross a collapsed road destroyed by heavy rain in Higashihiroshima in Hiroshima Prefecture on Saturday. In Kurashiki, Okayama Prefecture, city officials said it was hard to determine how many residents were actually missing.