Flavored electronic cigarettes linked to possible cardiovascular disease

GETTY    
   VAPERS BEWARE Smoking e-cigarettes might not be as safe as people thought

Lead author Jessica Fetterman of the Boston University School of Medicine said, 'Our research suggests that the flavouring additives on their own impart toxicity, and that's really alarming'.

Nitric oxide is a key component that lowers inflammation across the body, prevents clotting, and ensures that blood vessels are flexible enough to withstand greater blood flow.

Short-term exposure to certain flavorings used in electronic cigarettes and other tobacco products proved toxic to endothelial cell function in laboratory studies, suggesting that the flavor additives could impair blood vessel function over time and contribute to heart damage.

Scientists have been sprinting to determine the short and long term effects of vaping and e-cigarette use at the rate that these products are being adopted among teens and young adults.

Because e-cigarettes have only existed since 2007, little is known about their long-term effects.

There is a public perception that flavored e-cigarettes are harmless or at least less harmful than traditional cigarettes, but researchers at the Boston University School of Medicine say e-cigs may pose significant health risks.

She explained: "Increased inflammation and a loss of nitric oxide are some of the first changes to occur leading up to cardiovascular disease and events like heart attacks and stroke, so they are considered early predictors of heart disease". Although numerous flavorings used to produce the flavors have been determined to be safe in food products, the long-term safety for inhalation into the lungs is not known.

After being exposed to the cells for just 90 minutes, all nine flavors-menthol (mint), acetylpyridine (burnt flavor), vanillin (vanilla), cinnamaldehyde (cinnamon), eugenol (clove), diacetyl (butter), dimethylpyrazine (strawberry), isoamyl acetate (banana) and eucalyptol (spicy cooling)-were unsafe to the epithelial cells and caused cell deathwhen used at the highest levels. At lower levels, cinnamon, clove, strawberry, banana and spicy cooling had a similar effect. However, lower concentrations of selected flavors (vanillin, menthol, cinnamaldehyde, eugenol, and acetylpyridine) induced both inflammation and impaired A23187-stimulated nitric oxide production.

Fetterman agreed, and said that the next step will be to directly examine e-cigarette users. They also found that endothelial cells from smokers showed the same toxicity as those treated with flavoring chemicals.

"While e-cigarettes contain nicotine, they seem to be far less addictive than cigarettes".

"Most of the harmful chemicals in cigarette smoke aren't present in e-cigarettes".

"That's really the big concern, that kids are going to become hooked on [these products]" said Fetterman. Flavored tobacco products are a major driver of experimentation among youth.

Related:

Comments

Latest news

Ambati Rayudu to be dropped from England tour after failing Yo-Yo test
Rayudu's failure to clear the fitness test looks set to result in his omission from the squad that will travel to England . Youngster Sanju Samson, too, could not clear the test and was left out of India A's squad for its tour of England .

Technology helps France to 2-1 win over Australia
But the team of VAR officials had a look at the incident and decided after multiple replays that Griezmann had indeed been fouled. Didier Drogba is backing Paul Pogba to deliver for both Manchester United and France .

These 15 US Cities Are Hot Spots for Unvaccinated Kids
The 12 states are Arkansas, Arizona, Idaho, Maine, Minnesota , North Dakota, Ohio, Oklahoma, Oregon, Pennsylvania, Texas and Utah. In recent years, multiple outbreaks of measles - once considered eliminated by the CDC in 2000 - have popped up.

Johanna Konta through to Nottingham Open semi-finals
Evans was one of two British players hoping to make the last four but James Ward fell 6-4 6-3 to Ilya Ivashka . Watson made the better start to the second and led 4-1 but Konta fought back and edged a close tie-break.

In Merkel migrant row, Germans back tough policies
There was no immediate deal in sight after a "crisis meeting" on Thursday night. There appeared to be few avenues left on Wednesday for Mr.

Other news