At the same time, Pompeo offered Iran a series of dramatic potential US concessions if it agrees to make "major changes".
"The sting of sanctions will only grow more painful if the regime does not change course from the unacceptable and unproductive path it has chosen for itself and the people of Iran", Pompeo said. Given that United States trade with Iran is only about $300 million, other trading partners are more important for the full impact of sanctions to be felt.
In a video-message to the May 5 Iran Freedom Convention for Human Rights and Democracy in Washington, Mrs. Rajavi said the Iranian people "are calling on the worldwide community, in particular the West, to support their uprising for the overthrow of the Iranian regime".
"The US Secretary of State's yesterday speech was a physiological war against Iran rather than a politically motivated move", Razi Haji-Aqamiri told Trend on May 22.
"We will apply unprecedented financial pressure on the Iranian regime".
Europeans say that Pompeo's speech does not leave much room for negotiating with Iran.
It should be clear by now that Iranian regime's pursuit of nuclear weapons will only be definitively resolved once that regime is no longer in power. It must cease any uranium enrichment and withdraw its forces from Syria.
Pompeo gave no ground to European countries and companies to ease the impact of sanctions. Pompeo also cautioned European firms against continuing to do business in Tehran, toughening up the United States policy line after its withdrawal from the 2015 nuclear pact this month despite intense diplomatic efforts by Washington's European allies.
British Foreign Secretary Boris Johnson at Palacio San Martin during the G20 foreign ministers' meeting on May 21, 2018, in Buenos Aires.
In another departure from the Obama administration's approach, Pompeo said that "a treaty is our preferred way to go". He said the prospect for a new deal "is going to be very, very hard".
Not surprisingly, Iran rejected Pompeo's demands as well.
GETTYIranian President Hassan Rouhani
But Mogherinicalled on the USA to keep its commitments as part of the agreement signed under Trump's predecessor Barack Obama.
"The essence of radicalism passes by fast", Heshmatollah Falahatpisheh told the Iranian Students News Agency. He said Iran would "allow for this era of extremism to pass".
US President Donald Trump's newly installed top diplomat also hinted at the possibility of military action should Iranian leaders reconstitute their nuclear program. Instead, Trump wants North Korea to give up everything first.
Iran was deemed in compliance of the JCPOA, including by the Trump administration.
The differences between the two are significant.
"This deal belongs to the global community, having been endorsed by the United Nations Security Council".
Shaikh Khalid has also charged that Iran exploited extremist groups, provided safe haven for fugitives, opened training camps for terrorist groups and smuggled arms and explosives in quantities that were enough to demolish entire cities.
The US was able to prod countries-most importantly China-into cutting off economic activity, contributing to North Korea's new willingness to consider concessions.
"Can the European Union guarantee effective banking transactions with Iran?"
Israeli Prime Minister Benjamin Netanyahu on Tuesday hailed the United States's policy on Iran and urged the rest of the world to follow suit. "It will not have the resources to do both", Pompeo said.
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