West Bromwich took the attacking initiative and were denied an early goal as David De Gea brilliantly saved Jack Livermore's curled shot in the 12th minute.
United can get a stronghold on second place with a victory while a home win would also virtually seal relegation for the Baggies.
The setup provided Pogba more creative freedom and showed the damage he could do with such license in the derby win. Most notably, Lukaku scored a hat-trick in his final appearance for the Midlands club in an eventful 5-5 draw against United, in Sir Alex Ferguson's last game in charge of the Reds.
The 24-year-old, meanwhile, has gone from strength to strength following his stint at West Brom, enjoying a goal-laden spell with Everton before joining Manchester United last summer in a deal worth a reported £75million plus add-ons.
West Brom will be missing the services of midfielders Gareth Barry (knee) and James Morrison (calf), both of whom are ruled out for the rest of the season.
United produced a subdued performance against the Baggies and were beaten by a 73rd-minute header from Jay Rodriguez. West Brom are the bottom team and that indicates how important and decisive the game will be for them; they need points.
Former England global Gary Lineker, who now work as a television presenter, tweeted: "Congratulations to @ManCity on winning the Premier League title". The Northern Irishman attracted interest from the Premier League giants in January, but neither managed to reach a transfer agreement with the west Midlands club. "Our City. Premier League Champions 17/18".
The 2012 title win had the infamous last-gasp goal by Sergio Aguero.
"I was talking before the game and I was saying the first time you win it you feel you are going to win all of them and the first time you lose it you feel like you are never going to win it again, so you want to hold on to this feeling". I wouldn't be happy if I was tells (sic) I won the title because someone else lost the match.
"That's why winning next week, hopefully we will, it will remain in our hearts forever".
Fortis board says unable to engage with IHH
In addition, the company has also received a non-binding expression of interest from IHH Healthcare Bhd, the statement said. IHH in its letter to the company's Board on April 11, 2018 made an offer of Rs 160 per Fortis share.
Morgan Stanley Trims CH Robinson (CHRW) Target Price to $68.00
Lpl Financial Llc decreased its stake in Magna Intl Inc (MGA) by 13.91% based on its latest 2017Q4 regulatory filing with the SEC. This signal may indicate if the Buy or Sell is weakening or gaining strength, or if the Hold is leaning towards a Buy or Sell.
Crash closes Hwy. 400 in Barrie
Kerry Schmidt said one tractor-trailer ended up in the ditch while another crashed into the guardrail. The northbound lanes are expected to open before southbound lanes, but no timeline has been given.