Second seed Edmund was playing in his first ATP Tour final but was no match for Andujar who repeated his triumphs of 2011 and 2012 when the event was staged in Casablanca.
He's now 13 spots away from matching his career-high of No. 53, which he reached in 2016, his first year on the ATP World Tour.
A second break followed as the Spaniard stormed to a 4-1 lead and although the Brit did briefly reduce the deficit, Andujar made no mistake in securing the title.
"It was a good tournament, it was great experience for me", said Edmund on the ATP Tour's official website. "It's been a good year so far, it's not the result I wanted, but nevertheless a good week for me".
Edmund will return to action in the coming days as he takes on Italy's Andreas Seppi in the first round of the Monte-Carlo Masters.
But he was up against it early on, broken in his first game and then twice more as Andujar raced to the first set.
The Spaniard said: "I played very well during the whole match, trying to make him move as much as I could. I was very solid today".
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