Aiming to save her best for the February 21 downhill at the Pyeongchang Olympics, Vonn has had only one win this season a super-G in Val d'Isere, France, more than a month ago.
Vonn crushed the course with an error-free run that made her the oldest female athlete to win a World Cup downhill, and she did it by almost a full second over Tina Weirather of Liechtenstein.
"I know what I'm capable of. We're very different. We're really exact opposites", Vonn said. "No matter what happens from here to the Olympics I'll be confident".
"I'm not anxious about my knees", said Vonn, who was also fastest in Wednesday and Thursday training runs by almost a second.
"I'm really happy", Vonn said in the post-race news conference.
Vonn also won Super G bronze in Vancouver but missed the 2014 Sochi Games with a knee injury and is taking no risks this time.
Vonn stepped up her preparations for next month's Winter Olympics in Pyeongchang with a flawless effort to finish 0.92 seconds ahead of Weirather and 0.98 seconds in front of Wiles for her 40th downhill victory. A complicated algorithm triggers inflation during falls when skiers reach a point where they can no longer regain control.
"It was good, clean skiing today".
It was Vonn's second win of the season, following a downhill victory at Val d'Isere, France, on December 16, and it was the second day in a row that the Americans took two spots on the podium.
"I'm excited", Vonn said of Sunday's super-G. "I had to pull out the superpowers for today".
Mikaela Shiffrin warned she wants to prove that her maiden World Cup downhill win in Lake Louise was no fluke as she challenges speed queen Lindsey Vonn in Saturday's second downhill at Cortina d'Ampezzo.
Vonn has said she will continue to race until she breaks Stenmark's record.
Shiffrin, Vonn and Wiles are third, fifth and seventh in the downhill standings, respectively. There will be no holding back.
"That's what I'm working on with my equipment right now".
"The tactics leading into the Olympics are so that I can get to the Olympics healthy - not that I'm afraid to push myself in bad conditions", Vonn added.
"I just like to have fun and I like to travel - and I love skiing. It's all or nothing in Korea".
Wiles was skiing just off Vonn's pace at the top intervals but almost overcooked a turn after catching a rut.
Wiles, 25, qualified for her second straight Olympic team after bursting onto the U.S. Ski Team in by winning the U.S. downhill title at Copper Mountain in Colorado in 2013 and 2014. And for Vail's Lindsey Vonn, it has been the scene of great success.
"She's done a lot for my career and she gave me an wonderful course report and pumped me up through the radio before my run", Wiles said.
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"I think I was well prepared and I stuck with my plan and I'm glad as I can stand here as a victor today", Berdych said on court. On Margaret Court, it was No17 seed and US Open runner-up, Madison Keys against 25-year-old Ana Bogdan, ranked 104.
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In comparison, Paes and Raja were broken four times out of seven opportunities that were created by the Brit-Brazilian pairing. It was in 2012, when Leander had last won the Australian Open with Radek Stepanek by beating Bryan Brothers of the US.