Cutler is hopeful that neratinib, which was approved in the extended adjuvant setting in breast cancer in July, can provide clinical benefit to the rare liver cancer patient population and, in this video, he explains why.
MONALEESA-7 investigated efficacy and safety of Kisqali in combination with tamoxifen or non-steroidal aromatase inhibitor plus goserelin in premenopausal or perimenopausal women with hormone-receptor positive, human epidermal growth factor receptor-2 negative (HR+HER2-) advanced breast cancer.
Hershman's team wondered if the ancient practice of acupuncture might help.
Novartis is looking for an expanded combination therapy label for its Kisqali after a trial showed it halts progression of an aggressive kind of breast cancer in younger women for longer than standard drugs.
"This is yet another study that reveals the benefits of acupuncture in treating pain", Coomer said. The BPI is a self-administered 14-item questionnaire created to assess pain on a scale from zero to 10, where higher scores indicate more pain. The patients were monitored for another 12 weeks after stopping acupuncture treatments, and reported on their pain using various methods, including the BPI, throughout this 24-week period.
"If something so simple as acupuncture can improve upon these symptoms and the patients' quality of life, we will have more women becoming compliant in taking their medication, and one would expect improved outcomes", Cassell added. Of the patients in the study, 110 received true acupuncture, 59 were given fake acupuncture - needles placed at ineffective spots on the body - and another 57 were placed on a waiting list.
The study had a median follow-up of 46.1 months, during which time 264 patients had a recurrence, diagnosis of a new breast cancer, diagnosis of a new cancer outside the breast, or died. "We need to identify strategies to control these side effects, the most common of which is debilitating joint pain and stiffness".
Breastcancer.org has more on aromatase inhibitors. "We have a huge problem in this country with pain medications, and it's imperative to find alternative ways of controlling pain and discomfort so that individuals with breast cancer can stay on their treatment".
FIRST ALERT Weather Day for snow potential on Friday
Even colder air will arrive Friday, and it could be cold enough for the rain to switch over to a wintry mix across the midstate. A cold rain mixed with sleet pellets is expected during the day on Thursday, with temperatures staying in the 40s all day.
B-1B, F-22 jets hold attack drills in Korea
White House national security adviser HR McMaster stated that the chances for war on the Korean Peninsula grow daily. According to reports , the US 7th Air Force deployed six F-22 and 18 F-35 stealth fighter jets for the exercise.
Jet Airways Q2 net profit nosedives 91% to Rs 50cr
In a later note, the airline said it had made a profit of Rs 190.22 crore a year ago on the sale and leaseback of planes. At 10:20 AM; it was trading at 3% lower at Rs 675 against 0.71% rise in the benchmark index.