The pilot, whose name was not released, is with the District of Columbia Air National Guard and was flying one of four fighter jets from Maryland to a shooting range in Pennsylvania for a training exercise when the crash happened.
An Air Force official, speaking on condition of anonymity because the incident was so recent, said the jet that went down was an F-16 from the Air National Guard's 113th Fighter Wing.
"That ride on those rocket rails was the smoothest ride I've ever taken in my life", said retired Air Force Lt. Col. Dick Rutan.
Brady said one pilot parachuted out.
Prince George's County fire department spokesman Mark Brady tells WRC-TV that one pilot parachuted out of the aircraft and was picked up by a military helicopter.
Crystal Hollingsworth said pieces of the plane fell in her neighbor's yard, damaging some of the home's siding. "And then I heard a second boom, but it was so loud", one resident said. "My house shook, like an quake".
The plane appears to have gone down in an area that was not populated, Brady said.
ABC News said the pilot ejected in "an unpopulated area" and "is OK" according to an official. The altitude of the jet when he ejected is unknown.
The 113th Wing guards the U.S. against threats by air. They are one of the busiest wings in the country, with as many as 3,000 flights per year guarding Washington's airspace.
The aircraft is believed to be an F-16, NBC News' Tom Costello reported.
Information was not immediately available on whether the pilot was taking off or landing. Homes near the scene have been evacuated as a precaution due to the possibility of hazardous materials and some roads are closed in the area. Authorities are knocking on the doors of homes and are alerting residents.
Reginald Stewart said neighbors called to tell him that a plane had crashed and that debris had hit his house. He said he could "not confirm if [the aircraft] hit anything on the ground".
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